Clinical Efficacy and Biomechanical Behavior of Different Compression Systems in Venous Ulcers: Pressure, Stiffness and Healing

INTRODUCTION: Venous leg ulcers are the most severe manifestation of chronic venous insufficiency, and their treatment is based on compression therapy, whose effectiveness depends on the magnitude of the pressure and the biomechanical properties of the system. Doubts persist about the actual correlation between interface pressure, bandage stiffness and clinical outcomes in real-world practice. OBJECTIVE: To compare the clinical efficacy and biomechanical behavior of different multicomponent compression systems in venous leg ulcers, analyzing the relationship between interface pressure, static stiffness, edema reduction and variation in the wound area. METHODOLOGY: at three points on the leg for 96 h, recording final pressure, static stiffness, perimeters and ulcer area. RESULTS: All systems achieved a reduction in leg circumference, more marked at the proximal points, evidencing an overall decongestant effect. The correlation between final pressure and edema reduction was weak, and relevant differences were observed in the reduction in ulcer area, with Urgo K2 and CPK Compress 2 standing out with decreases of more than 50% compared to medium or low yields of other systems with comparable pressures. The static stiffness analysis showed specific patterns according to system and leg size, as well as a heterogeneous longitudinal distribution of pressure. CONCLUSIONS: The efficacy of compression in venous ulcers depends on both the interface pressure and the design and biomechanical behavior of the system, with clinically relevant differences between multicomponent dressings. Multipoint pressure and stiffness monitoring provides useful information to optimize system selection and support decisions based on biomechanical parameters and standardized clinical outcomes.

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Journal
Life
Published
2026-04-01
DOI
https://doi.org/10.3390/life16040585
Primary Topic
Diagnosis and Treatment of Venous Diseases
Type
article
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article

Clinical Efficacy and Biomechanical Behavior of Different Compression Systems in Venous Ulcers: Pressure, Stiffness and Healing

Juan Francisco Jiménez García, Francisco Pedro García Fernández, María Piedad García Ruíz, José Luis Jiménez Láinez et al.
Life
Diagnosis and Treatment of Venous Diseases
article

Clinical Efficacy and Biomechanical Behavior of Different Compression Systems in Venous Ulcers: Pressure, Stiffness and Healing

Juan Francisco Jiménez García, Francisco Pedro García Fernández, María Piedad García Ruíz, José Luis Jiménez Láinez, Ana Belén Fernández Ramírez, María Gutiérrez García, Mercedes Muñoz Condez
article en

Abstract

INTRODUCTION: Venous leg ulcers are the most severe manifestation of chronic venous insufficiency, and their treatment is based on compression therapy, whose effectiveness depends on the magnitude of the pressure and the biomechanical properties of the system. Doubts persist about the actual correlation between interface pressure, bandage stiffness and clinical outcomes in real-world practice. OBJECTIVE: To compare the clinical efficacy and biomechanical behavior of different multicomponent compression systems in venous leg ulcers, analyzing the relationship between interface pressure, static stiffness, edema reduction and variation in the wound area. METHODOLOGY: at three points on the leg for 96 h, recording final pressure, static stiffness, perimeters and ulcer area. RESULTS: All systems achieved a reduction in leg circumference, more marked at the proximal points, evidencing an overall decongestant effect. The correlation between final pressure and edema reduction was weak, and relevant differences were observed in the reduction in ulcer area, with Urgo K2 and CPK Compress 2 standing out with decreases of more than 50% compared to medium or low yields of other systems with comparable pressures. The static stiffness analysis showed specific patterns according to system and leg size, as well as a heterogeneous longitudinal distribution of pressure. CONCLUSIONS: The efficacy of compression in venous ulcers depends on both the interface pressure and the design and biomechanical behavior of the system, with clinically relevant differences between multicomponent dressings. Multipoint pressure and stiffness monitoring provides useful information to optimize system selection and support decisions based on biomechanical parameters and standardized clinical outcomes.

LifeVol. 16(4)
Universidad de Granada (ES), Universidad de Jaén (ES), Complejo Hospitalario de Jaén (ES), University of Almería (ES), Universidad de Málaga (ES)
Good health and well-being
Openalex Percentile: Top 35%
Diagnosis and Treatment of Venous Diseases
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