Co-Cultivation of Cross-Kingdom Microorganisms Effectively Triggers the Production of Tryptophol and Its Heterologous Expression in E. coli
C41 to address the drawbacks of chemical synthesis. These findings combine co-cultivation with genetic engineering for tryptophol biosynthesis, expanding its antitumor application and laying a foundation for its industrial and sustainable production.
Authors
- Jeffrey S. Ren (ORCID: https://orcid.org/0000-0002-6989-8408)
- Jine Li
- Xiulei Xia
- Huarong Tan (ORCID: https://orcid.org/0000-0002-8842-9092)
- Yue Li
Institutions
- Capital Medical University (CN)
- Chinese Academy of Sciences (CN)
- Institute of Microbiology (CN)
- Beijing Obstetrics and Gynecology Hospital (CN)
Publication Details
- Journal
- Microorganisms
- Published
- 2026-04-01
- DOI
- https://doi.org/10.3390/microorganisms14040798
- Primary Topic
- Microbial Natural Products and Biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Chinese Academy of Sciences
- Tianjin University
- Tianjin University of Science and Technology
- Institute of Microbiology, Chinese Academy of Sciences