Detection of persistent viremia by a live attenuated vaccine strain of the chikungunya virus in a blood donor
We report here the case of a blood donor who tested positive for chikungunya RNA by nucleic acid testing introduced in Guadeloupe (a French island in the Caribbean) to prevent the transmission of arboviral infections by transfusion. The strain was isolated, and further investigations revealed the presence of the IXCHIQ live attenuated vaccine strain in blood 1 month after vaccination.
Authors
- Gilda Grard (ORCID: https://orcid.org/0000-0002-6088-2581)
- Pierre Gallian (ORCID: https://orcid.org/0000-0002-3310-5808)
- Syria Laperche (ORCID: https://orcid.org/0000-0002-6497-0108)
- Pierre Tiberghien (ORCID: https://orcid.org/0000-0002-9310-8322)
- S. Bégué
- Thierry Peyrard (ORCID: https://orcid.org/0000-0002-7715-568X)
- Khalil Helzy
- Laura Pezzi
- Damien Vainqueur
- Xavier de Lamballerie
- Géraldine Piorkowski
- Raphaelle Klitting
- Guillaume André Durand
Institutions
- Inserm (FR)
- Aix-Marseille Université (FR)
- Institut de Neurosciences des Systèmes (FR)
- Établissement Français du Sang (FR)
- Centre Hospitalier Universitaire Pointe-à-Pitre (GP)
- Institut de Recherche pour le Développement (FR)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2026-04-03
- DOI
- https://doi.org/10.1016/j.ijid.2026.108681
- Citations
- 1
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 24.91