Systematic Review and Meta-Analysis of Tuina as an Adjuvant Therapy for Functional Constipation in Children

up to 96%), wide prediction intervals that crossed the null value for all three primary outcomes, methodological limitations of the included studies (e.g., lack of blinding, unclear randomization), and short follow-up periods (most ≤2 months), these findings should be interpreted as exploratory rather than definitive. Evidence on weekly stool frequency and adverse reactions remains inconclusive. High-quality, long-term trials with standardized outcome measures and rigorous blinding are needed to validate these preliminary findings.