Comparison of BD MAX and GeneXpert for rapid detection of tuberculosis and rifampin–isoniazid resistance

Evaluated in 87 respiratory specimens, BD MAX showed 100% sensitivity and 90.3% specificity in AFS-positive samples (n = 56). In 31 AFS-negative/Xpert Ultra-positive cases, it detected 25 of 29 culture-positive cases. Among these respiratory specimens, BD MAX correctly identified isoniazid resistance in all six HR-TB cases.

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Publication Details

Journal
Journal of Microbiology Immunology and Infection
Published
2026-04-01
DOI
https://doi.org/10.1016/j.jmii.2026.03.008
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00

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article

Comparison of BD MAX and GeneXpert for rapid detection of tuberculosis and rifampin–isoniazid resistance

Yun-Shan Lu, Chun-Li Lee, Xiang-Jun Chen, Chin-Chung Shu et al.
Journal of Microbiology Immunology and Infection
Tuberculosis Research and Epidemiology
article

Comparison of BD MAX and GeneXpert for rapid detection of tuberculosis and rifampin–isoniazid resistance

Yun-Shan Lu, Chun-Li Lee, Xiang-Jun Chen, Chin-Chung Shu, Yu-Tsung Huang, Yu-Cheng Lin, Tai-Fen Lee
article en

Abstract

Evaluated in 87 respiratory specimens, BD MAX showed 100% sensitivity and 90.3% specificity in AFS-positive samples (n = 56). In 31 AFS-negative/Xpert Ultra-positive cases, it detected 25 of 29 culture-positive cases. Among these respiratory specimens, BD MAX correctly identified isoniazid resistance in all six HR-TB cases.

Journal of Microbiology Immunology and Infection
National Taiwan University Hospital (TW)
College of Medicine, National Taiwan University
Good health and well-being
Openalex Percentile: Top 20%
Tuberculosis Research and Epidemiology
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