Correlates of Anti-Toxoplasma IgG Antibodies in Females with Borderline Personality Disorder: A Pilot Cross-Sectional Study

Background: IgG seropositivity with the severity of BPD symptoms among adult females with BPD. Methods: -tests. Results: IgG antibodies. Although none of the hypothesized differences reached statistical significance, several medium-sized effects indicated potentially clinically relevant differences between the seropositive and seronegative groups. Specifically, the seropositive group reported more suicidal ideations during the past year (d = 0.67) and exhibited less severe symptoms of abandonment (d = 0.67) and depression (d = 0.57). The remaining symptoms showed small (suicidality, aggression, anger, and anxiety) or marginal (overall BPD severity, impulsivity) differences between the two groups. Conclusion: IgG seropositivity among patients with BPD than previously expected. Although the findings were not statistically significant, several trends indicated that seropositive patients might differ from the seronegative group. These preliminary results should be viewed as hypothesis-generating and validated in larger samples.