Cell-Type-Resolved Acetylation Regulator Atlas Defines Immune Endotypes and Druggable Vulnerabilities in Psoriasis
This integrative atlas links acetylation regulators to specific immune compartments, defines acetylation endotypes associated with distinct inflammatory programs, and provides a rationale for stratified epigenetic target selection in psoriasis.
Authors
- Le Kuai (ORCID: https://orcid.org/0009-0003-3228-9144)
- Xiaoya Fei
- Jiankun Song
- Yue Luo (ORCID: https://orcid.org/0000-0003-3498-4821)
- Miao Li (ORCID: https://orcid.org/0000-0003-1783-6341)
- Yi Ru
- Yonghua Su
- Mengji Xie
- Yanwei Xiang
- Xiaojie Ding
- Ruiping Wang
- Mi Zhou
- Ying Zhang
- Guoshu Deng
- Xiaoxuan Ma
- Bin Li
Institutions
- Tongji University (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Yueyang Hospital (CN)
- Shanghai Skin Disease Hospital (CN)
Publication Details
- Journal
- Biomedicines
- Published
- 2026-04-01
- DOI
- https://doi.org/10.3390/biomedicines14040804
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China