Seronegative Doege-Potter syndrome in a patient with a pleural-based solitary fibrous tumour

Doege-Potter syndrome (DPS) is a paraneoplastic syndrome characterised by episodic hypoglycaemia associated with solitary fibrous tumours (SFTs). It is thought to occur secondary to the secretion of a prohormone of insulin-like growth factor II by the tumour. Here we describe the diagnosis and management of a rare case of seronegative DPS in a patient with a pleural-based SFT.

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Publication Details

Journal
BMJ Case Reports
Published
2026-04-01
DOI
https://doi.org/10.1136/bcr-2025-270532
Primary Topic
Soft tissue tumor case studies
Type
article
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article

Seronegative Doege-Potter syndrome in a patient with a pleural-based solitary fibrous tumour

Nemer El Mouallem, Jason Reardon, Rithvik Reddy Nalamalapu
BMJ Case Reports
Soft tissue tumor case studies
article

Seronegative Doege-Potter syndrome in a patient with a pleural-based solitary fibrous tumour

Nemer El Mouallem, Jason Reardon, Rithvik Reddy Nalamalapu
article en

Abstract

Doege-Potter syndrome (DPS) is a paraneoplastic syndrome characterised by episodic hypoglycaemia associated with solitary fibrous tumours (SFTs). It is thought to occur secondary to the secretion of a prohormone of insulin-like growth factor II by the tumour. Here we describe the diagnosis and management of a rare case of seronegative DPS in a patient with a pleural-based SFT.

BMJ Case ReportsVol. 19(4)
Virginia Commonwealth University (US)
Openalex Percentile: Top 23%
Soft tissue tumor case studies
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Seronegative Doege-Potter syndrome in a patient with a pleural-based solitary fibrous tumour — Nemer El Mouallem, Jason Reardon, et al. · BMJ Case Reports (2026) | TGRS Research Map | TGRS