The Association of Periodontitis with Circadian Rhythm Disorders and Sleep—A Scoping Review

: Circadian rhythm alterations and poor sleep are related to periodontitis. A causal relationship between circadian rhythm disturbances, poor sleep, and periodontitis remains unclear, especially because of the cross-sectional design of most studies. No study has conducted an analysis of the reverse causality. To clarify this correlation, longitudinal studies should be conducted. A few experiments suggested that circadian rhythm disturbances and sleep deprivation induce periodontitis. Assessing direct causality and understanding the precise role of circadian rhythm alterations and sleep quality on periodontitis can lead to personalizing the management of the condition.

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Publication Details

Journal
Medicina
Published
2026-03-31
DOI
https://doi.org/10.3390/medicina62040662
Primary Topic
Oral microbiology and periodontitis research
Type
article
Field-Weighted Citation Impact
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article

The Association of Periodontitis with Circadian Rhythm Disorders and Sleep—A Scoping Review

Andrea Blasi, Marco Mascitti, Mariacristina Amato, Gaetano Isola et al.
Medicina
Oral microbiology and periodontitis research
article

The Association of Periodontitis with Circadian Rhythm Disorders and Sleep—A Scoping Review

Andrea Blasi, Marco Mascitti, Mariacristina Amato, Gaetano Isola, Angela Angjelova, Elena Jovanova, Gianluca Martino Tartaglia, Alessandro Polizzi
article en

Abstract

: Circadian rhythm alterations and poor sleep are related to periodontitis. A causal relationship between circadian rhythm disturbances, poor sleep, and periodontitis remains unclear, especially because of the cross-sectional design of most studies. No study has conducted an analysis of the reverse causality. To clarify this correlation, longitudinal studies should be conducted. A few experiments suggested that circadian rhythm disturbances and sleep deprivation induce periodontitis. Assessing direct causality and understanding the precise role of circadian rhythm alterations and sleep quality on periodontitis can lead to personalizing the management of the condition.

MedicinaVol. 62(4)
Marche Polytechnic University (IT), University of Milan (IT), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT), University of Catania (IT), Federico II University Hospital (IT), University of Naples Federico II (IT)
No poverty
Openalex Percentile: Top 36%
Oral microbiology and periodontitis research
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