Silent Stroke in Adult Cardiac Surgery: Mechanisms, Clinical Impact, and Preventive Strategies

: Silent stroke represents the most frequent form of neurological injury in adult cardiac surgery. Evidence suggests that these covert lesions reflect clinically meaningful cerebral injury, with potential short- and long-term consequences. Recognition of silent stroke as a relevant neurological endpoint supports a shift toward multimodal, perfusion-driven neuroprotective strategies and the routine incorporation of MRI-based outcomes in future cardiac surgical research.

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Publication Details

Journal
Medicina
Published
2026-04-01
DOI
https://doi.org/10.3390/medicina62040675
Primary Topic
Cardiac and Coronary Surgery Techniques
Type
article
Field-Weighted Citation Impact
0.00

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article

Silent Stroke in Adult Cardiac Surgery: Mechanisms, Clinical Impact, and Preventive Strategies

Robert Kalimi, Sotirios Prapas, Giorgia Falco, Antonio Totaro et al.
Medicina
Cardiac and Coronary Surgery Techniques
article

Silent Stroke in Adult Cardiac Surgery: Mechanisms, Clinical Impact, and Preventive Strategies

Robert Kalimi, Sotirios Prapas, Giorgia Falco, Antonio Totaro, Konstantinos Katsavrias, Salvatore Condello, Antonio Maria Calafiore, Michele Dell’Aquila, Augusto D’Onofrio, Youssef El Dsouki, Ignazio Condello, Mario Gaudino, Joshua Newman, Nirav Patel
article en

Abstract

: Silent stroke represents the most frequent form of neurological injury in adult cardiac surgery. Evidence suggests that these covert lesions reflect clinically meaningful cerebral injury, with potential short- and long-term consequences. Recognition of silent stroke as a relevant neurological endpoint supports a shift toward multimodal, perfusion-driven neuroprotective strategies and the routine incorporation of MRI-based outcomes in future cardiac surgical research.

MedicinaVol. 62(4)
University of Insubria (IT), University of Rome Tor Vergata (IT), University of Molise (IT), Northwell Health (US), Cornell University (US), Maastricht University (NL), Istituti Clinici Scientifici Maugeri (IT), Northwell Health Orthopaedic Institute (US), Henry Dunant Hospital (GR), Polyclinic General Hospital (GR), Weill Cornell Medicine (US)
Northwell Health
Openalex Percentile: Top 37%
Cardiac and Coronary Surgery Techniques
DOIOpen Access PDFOpenAlex
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Silent Stroke in Adult Cardiac Surgery: Mechanisms, Clinical Impact, and Preventive Strategies — Robert Kalimi, Sotirios Prapas, et al. · Medicina (2026) | TGRS Research Map | TGRS