Denosumab Offers Relatively Lower Initial Protection Against Osteoporotic Vertebral Fractures in Treatment‐Naive Patients Compared With Zoledronate
. Additionally, among patients with prior steroid exposure, Dmab users had a higher risk of osteoporotic fractures compared with ZOL users. In treatment-naive patients with osteoporosis, Dmab provided less initial protection against osteoporotic and vertebral fractures than ZOL, and delayed dosing further increased fracture risk.
Authors
- Shun‐Fa Yang (ORCID: https://orcid.org/0000-0002-0365-7927)
- Shiow‐Ing Wang (ORCID: https://orcid.org/0000-0003-3407-9020)
- Ko‐Hsiu Lu (ORCID: https://orcid.org/0000-0001-7600-4268)
Institutions
- Chung Shan Medical University Hospital (TW)
- Chung Shan Medical University (TW)
Publication Details
- Journal
- Clinical Pharmacology & Therapeutics
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1002/cpt.70270
- Citations
- 1
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 23.97