Single-Cell Gene Expression and eQTL Analyses in the Human Retina, RPE, and Choroid in Macular Degeneration
RNA in the RPE. We also identified an age-related decrease in complement inhibitors in the choriocapillaris, a tissue susceptible to complement mediated damage in AMD.
Authors
- Robert F. Mullins (ORCID: https://orcid.org/0000-0002-5006-0891)
- Andrew P. Voigt (ORCID: https://orcid.org/0000-0001-8107-8317)
- Lola Lozano (ORCID: https://orcid.org/0000-0002-0492-4759)
- Todd E. Scheetz (ORCID: https://orcid.org/0000-0002-1965-5811)
- Budd A. Tucker (ORCID: https://orcid.org/0000-0003-2178-1742)
- E Navratil (ORCID: https://orcid.org/0000-0002-8364-5108)
- Jeremy A. Lavine (ORCID: https://orcid.org/0000-0002-0884-1336)
- John H. Fingert (ORCID: https://orcid.org/0000-0002-0377-0479)
- Kelly Mulfaul (ORCID: https://orcid.org/0000-0003-4441-4806)
- Nathaniel K. Mullin (ORCID: https://orcid.org/0000-0003-4320-2852)
- Edwin M. Stone (ORCID: https://orcid.org/0000-0003-3343-4414)
- Miles J Flamme-Wiese
Institutions
- Northwestern University (US)
- University of Iowa (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-04-01
- DOI
- https://doi.org/10.64898/2026.03.30.714946
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health