Lineage-Specific Sex-Biased Transcriptional Programs in Healthy Human Truncal Skin Revealed by Single-Cell Transcriptomics

Sexual dimorphism in healthy human truncal skin is encoded through lineage-structured transcriptional regulation rather than broad compositional changes, providing a framework for understanding sex-biased skin homeostasis and disease susceptibility.

Authors

BinBin Lai
Yu Yang
Honghao Yu

Institutions

Peking University (CN)
Peking University First Hospital (CN)

Publication Details

Journal: Genes
Published: 2026-03-31
DOI: https://doi.org/10.3390/genes17040415
Primary Topic: Skin Protection and Aging
Type: article
Field-Weighted Citation Impact: 0.00

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article

Lineage-Specific Sex-Biased Transcriptional Programs in Healthy Human Truncal Skin Revealed by Single-Cell Transcriptomics

BinBin Lai, Yu Yang, Honghao Yu

Mar 31, 2026

Genes

Skin Protection and Aging

article

Lineage-Specific Sex-Biased Transcriptional Programs in Healthy Human Truncal Skin Revealed by Single-Cell Transcriptomics

BinBin Lai, Yu Yang, Honghao Yu

March 31, 2026article en

Abstract

GenesVol. 17(4)

Peking University (CN), Peking University First Hospital (CN)

Openalex Percentile: Top 33%

Skin Protection and Aging

DOI Open Access PDF OpenAlex

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Lineage-Specific Sex-Biased Transcriptional Programs in Healthy Human Truncal Skin Revealed by Single-Cell Transcriptomics — BinBin Lai, Yu Yang, et al. · Genes (2026) | TGRS Research Map | TGRS