In Silico Analyses Suggest That Exercise-Induced Irisin-Mediated Neuroprotection Supports Non-Pharmacological Preventive Strategies for Alzheimer’s Disease in Public Health
5 receptor, suggesting activation of neuroprotective pathways. The findings reinforce physical exercise as a strategic public health tool for the prevention of AD, providing an epidemiological and molecular basis to reduce the future burden of the disease, thereby shifting the focus of public health policy from treatment to prevention.
Authors
- Aline Sampaio Cremonesi (ORCID: https://orcid.org/0000-0002-1283-1237)
- Moara Manias
- João Victor Rossetti Vieira
Institutions
- Universidade São Francisco (BR)
Publication Details
- Journal
- International Journal of Environmental Research and Public Health
- Published
- 2026-04-01
- DOI
- https://doi.org/10.3390/ijerph23040449
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00