Tourniquet Duration and Early Clinical and Biomarker Outcomes in Total Knee Arthroplasty: A Comparative Cohort Study
: Tourniquet times between 90 and 120 min were not associated with higher pain levels or more swelling, but an increased need for intravenous analgesia and a higher increase in pro-inflammatory markers. This might be a consequence of a more pronounced ischemia/reperfusion injury with tourniquet times longer than 90 min.
Authors
- Sandro Kohl (ORCID: https://orcid.org/0000-0002-1268-4732)
- Robert Rieben (ORCID: https://orcid.org/0000-0003-4179-8891)
- Emanuel F. Liechti (ORCID: https://orcid.org/0000-0003-2038-3515)
- Rolf Spirig (ORCID: https://orcid.org/0000-0002-0304-8726)
- Mai M. Abdelhafez (ORCID: https://orcid.org/0000-0002-4523-0286)
- Frank M. Klenke (ORCID: https://orcid.org/0000-0002-7115-5048)
- Alain Despont
- Nele Isabelle Pfeiffer
- Jelena Kummer
- Jane Penelope Shaw
Institutions
- University of Bern (CH)
- Bern University of Applied Sciences (CH)
- University Hospital of Bern (CH)
- CSL (Switzerland) (CH)
- October University of Modern Sciences and Arts (EG)
Publication Details
- Journal
- Journal of Clinical Medicine
- Published
- 2026-04-01
- DOI
- https://doi.org/10.3390/jcm15072675
- Primary Topic
- Blood transfusion and management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Bern
- Inselspital, Universitätsspital Bern
- Agroscope