May Watchful Waiting Strategy Be Benefit In Patients With Coronary Thrombus Receiving BEP Chemotherapy?

The relationship between the combination of bleomycin-etoposide-cisplatin, a chemotherapeutic treatment option used in testicular carcinomas, and acute thrombotic events has been previously described. Acute coronary syndromes associated with this treatment have been frequently reported. The differences in the underlying mechanisms that lead to coronary events suggest that the treatment options may vary in these situations. The decision regarding the right treatment option for the patient sometimes emerges after a relatively long process that requires patience. In this event, which occurs without atherosclerosis and involves vasospasm and thrombus formation, a conservative approach may be beneficial. A 42-year-old individual diagnosed with testicular cancer who did not have any cardiac risk factors was diagnosed with acute coronary syndrome. Since no atherosclerotic background is observed on coronary angiography, coronary intervention is postponed. In this case, the management of the patient will be discussed with a focus on medical treatment without any coronary intervention.

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Publication Details

Journal
Journal of Emergency Medicine Case Reports
Published
2026-03-31
DOI
https://doi.org/10.33706/jemcr.1713315
Primary Topic
Chemotherapy-induced cardiotoxicity and mitigation
Type
article
Field-Weighted Citation Impact
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article

May Watchful Waiting Strategy Be Benefit In Patients With Coronary Thrombus Receiving BEP Chemotherapy?

Tuğçe ÇÖLLÜOĞLU, Orhan Önalan, Fahri Çakan
Journal of Emergency Medicine Case Reports
Chemotherapy-induced cardiotoxicity and mitigation
article

May Watchful Waiting Strategy Be Benefit In Patients With Coronary Thrombus Receiving BEP Chemotherapy?

Tuğçe ÇÖLLÜOĞLU, Orhan Önalan, Fahri Çakan
article en

Abstract

The relationship between the combination of bleomycin-etoposide-cisplatin, a chemotherapeutic treatment option used in testicular carcinomas, and acute thrombotic events has been previously described. Acute coronary syndromes associated with this treatment have been frequently reported. The differences in the underlying mechanisms that lead to coronary events suggest that the treatment options may vary in these situations. The decision regarding the right treatment option for the patient sometimes emerges after a relatively long process that requires patience. In this event, which occurs without atherosclerosis and involves vasospasm and thrombus formation, a conservative approach may be beneficial. A 42-year-old individual diagnosed with testicular cancer who did not have any cardiac risk factors was diagnosed with acute coronary syndrome. Since no atherosclerotic background is observed on coronary angiography, coronary intervention is postponed. In this case, the management of the patient will be discussed with a focus on medical treatment without any coronary intervention.

Journal of Emergency Medicine Case ReportsVol. 17(1)
Adli Tıp Kurumu (TR), Department of Public Health (MM)
Good health and well-being
Openalex Percentile: Top 25%
Chemotherapy-induced cardiotoxicity and mitigation
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