Probing the Role of Accessory FeS Clusters in Putative Sensory Group D [FeFe] Hydrogenase: Influence of the C-Terminal [4Fe-4S] Cluster on the Reactivity of <i>Tam</i> HydS
-sensing or signaling function is unlikely to involve redox state changes in the C-terminal [4Fe-4S] cluster. Still, highly conserved charged residues around the [4Fe-4S] clusters of group D [FeFe] hydrogenases indicate a functional role of the C-terminal region.
Authors
- Ping Huang (ORCID: https://orcid.org/0000-0002-7676-6905)
- Gustav Berggren (ORCID: https://orcid.org/0000-0002-6717-6612)
- Conrad Schumann (ORCID: https://orcid.org/0009-0007-0847-1420)
- Princess R. Cabotaje (ORCID: https://orcid.org/0000-0002-0500-5981)
- Prasenjit Bhowmik (ORCID: https://orcid.org/0009-0004-7123-0011)
- Henrik Land
- Maximilian Böhm
Institutions
- Uppsala University (SE)
- BioMimetic Systems (United States) (US)
Publication Details
- Journal
- Biochemistry
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1021/acs.biochem.5c00784
- Primary Topic
- Metalloenzymes and iron-sulfur proteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Vetenskapsrådet
- Energimyndigheten
- HORIZON EUROPE European Innovation Council