Nitroxoline exerts potent anti- <i>Aspergillus fumigatus</i> activity by disrupting copper homeostasis and inducing oxidative stress
by perturbing copper homeostasis and inducing oxidative stress, highlighting its unique antifungal potential and providing a conceptual basis for metal-targeted therapeutic strategies against IPA and drug-resistant fungal infections.
Authors
- Dan Cao
- Yan Li (ORCID: https://orcid.org/0000-0001-9999-3249)
- Yiru Zhang
- Yanghui Xiang
- Xin Yuan
- Pusheng Xu
- Ying Zhang
- Yuxin Han
Institutions
- Collaborative Research Group (AU)
- National Centre for Infectious Diseases (SG)
Publication Details
- Journal
- Antimicrobial Agents and Chemotherapy
- Published
- 2026-03-31
- DOI
- https://doi.org/10.1128/aac.01831-25
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00