Delta Describe, the French Collaborative Project: The Profile and Management of Hepatitis Delta Patients in Metropolitan France
. Most patients knew the year of their delta diagnosis, and 69.1% knew their fibrosis stage. Liver-related events occurred in 14.3% (67/468) of patients, mainly comprising portal hypertension (61.6%), liver failure (12.3%), and hepatocellular carcinoma (26%), and 45 patients (45/468) underwent liver transplantation. At the time of the survey, 47.1% of the patients reported undetectable HDV RNA; 40.6% (222/547) had currently or previously undergone BLV treatment. Among patients receiving ongoing treatment for HDV at the time of the survey, 84.8% were receiving nucleos(t)ide analogs (NUCs). In metropolitan France, HDV patients had access to specialized follow-up care and innovative therapies (bulevirtide), were mostly on NUCs, and demonstrated good disease awareness.
Authors
- Céline Rigaud
- Isaac Fassler
- Ségolène Brichler (ORCID: https://orcid.org/0000-0002-7336-7730)
- Benoît Visseaux (ORCID: https://orcid.org/0000-0002-9279-5538)
- Pascale Trimoulet
- Dominique Roulot (ORCID: https://orcid.org/0000-0003-0926-3563)
- Cécile Brouard (ORCID: https://orcid.org/0000-0001-9771-7400)
- Stéphane Chevaliez (ORCID: https://orcid.org/0000-0001-6913-9017)
- Sonia Burrel (ORCID: https://orcid.org/0000-0002-7783-2601)
- Aurélie Guigon
- Anaïs Soares
- Vincent Quentin
- E Billaud
- S. Alain
- Veronique Loustaud-Ratti
- Marie Bosselut
- Karine Saune
- Dadi Abel Diédhiou
- Gérard Lina
- André-Jean Remy
- Paul Carrier
- Marianne Coste-Burel
- Marc Bourlière
- Jean-Pierre Bronowicki
- Delta Describe Study Group
- Hélène Fontaine
- Marilyne Debette-Gratien
- Anne-Marie Roque-Afonso
- Jacques Izopet
- Sandrine François
- Bernard Castan
- Katell Peoc’h
- Jérôme Boursier
Institutions
- Université de Bordeaux (FR)
- Inserm (FR)
- Université Fédérale de Toulouse Midi-Pyrénées (FR)
- Université Paris-Est Créteil (FR)
- Société Nationale des Chemins de Fer Français (France) (FR)
- Université de Lille (FR)
- Hôpital Beaujon (FR)
- Centre Hospitalier Universitaire de Nantes (FR)
- Société de Réanimation de Langue Française (FR)
- Lille’s Cardiology Hospital (FR)
- Université Sorbonne Paris Nord (FR)
- Santé Publique France (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hospices Civils de Lyon (FR)
- Bordeaux Population Health (FR)
- Hôpital Saint Joseph (FR)
- Centre d'Investigation Clinique de Nantes (FR)
- Hôpital Avicenne (FR)
- Hôpitaux Universitaires Henri-Mondor (FR)
- Association of French Motorway Companies (FR)
- Hôpitaux de Saint Maurice (FR)
- Ceramic Synthesis and Functionalization Laboratory (FR)
- Eurofins (France) (FR)
- Groupe Hospitalier Intercommunal Le Raincy Montfermeil (FR)
- Hôpital Paul-Brousse (FR)
- Université de Limoges (FR)
- HCL Technologies (India) (IN)
- Nantes Université (FR)
Publication Details
- Journal
- Viruses
- Published
- 2026-03-31
- DOI
- https://doi.org/10.3390/v18040424
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Gilead Sciences