Composition of Health Care Contact Days and Mortality Prediction Among Older Adult Clinical Trial Participants
PURPOSE: Contact days exceeding trial protocol-mandated care may represent adverse clinical events and portend worse outcomes. Identifying patients at risk of poor outcomes could enable clinical teams to intervene early and support patients' needs. MATERIALS AND METHODS: unplanned inpatient). Cox frailty landmark regression analysis was used in a random 60% training set to identify the optimal threshold (percentile) and landmark (months) for contact-day measures as the predictor based on the chi-square statistic. Candidate predictors were tested in the remaining 40% sample. RESULTS: = .014). CONCLUSION: One in five trial follow-up days was a health care contact day, of which the majority were unplanned ambulatory contact days. Meaningfully decreasing contact-day burdens will require addressing uncoordinated unplanned ambulatory contact days. The low threshold (≥1 in the first 2 months) of unplanned inpatient days in predicting mortality highlights the adverse impact of any acute care use on survival.
Authors
- Cathee Till (ORCID: https://orcid.org/0000-0002-6801-8333)
- Michael LeBlanc (ORCID: https://orcid.org/0000-0001-7192-2860)
- Joseph M. Unger (ORCID: https://orcid.org/0000-0002-5191-0317)
- Arjun Gupta
- D. L. Hershman
Institutions
- Fred Hutch Cancer Center (US)
- City of Hope (US)
- Columbia University (US)
Publication Details
- Journal
- JCO Oncology Practice
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1200/op-25-01182
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 0.00