Structural insights into target detection by the <i>S. marcescens</i> type III CRISPR complex and its deployment in SNP identification
transcript that are associated with sickle cell disease indicating an additional role for type III CRISPR systems in point-of-care diagnostics in low-resource settings.
Authors
- Terje Dokland (ORCID: https://orcid.org/0000-0001-5655-4123)
- Si Wu (ORCID: https://orcid.org/0000-0002-6346-7359)
- Anju Teresa Sunny
- Luqman O. Ajisafe
- Calvin Perdigao
- Jack A Dunkle
Institutions
- University of Alabama (US)
- University of Alabama at Birmingham (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-03-31
- DOI
- https://doi.org/10.64898/2026.03.30.715313
- Primary Topic
- CRISPR and Genetic Engineering
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health
- National Institute of General Medical Sciences