Developing a programme theory of a complex, home-based rehabilitation intervention for recovery after an episode of delirium

BACKGROUND: Delirium in older adults is associated with persistent cognitive and functional decline, increased institutionalisation, and higher mortality. Evidence-based strategies to support recovery after hospitalisation remain limited. This paper outlines the development and refinement of the programme theory underpinning RecoverED, a novel, home-based, multicomponent rehabilitation intervention designed to support post-delirium recovery. METHODS: We applied a realist-informed, multi-stage process to develop the RecoverED programme theory. This included a rapid realist review, qualitative interviews with older adults, carers, and healthcare professionals, an expert panel workshop, iterative programme theory meetings, and a process evaluation embedded within a single-arm feasibility trial. Data were synthesised into a logic model linking intervention components to hypothesised mechanisms and outcomes. RESULTS: The programme theory outlines how cognitive and physical rehabilitation, psychosocial support, health monitoring, lifestyle guidance, and delirium education are expected to promote recovery. Cognitive activities aim to rebuild executive function and daily independence; physical rehabilitation maintains mobility; psychosocial support reduces anxiety and promotes confidence; health monitoring and lifestyle guidance address comorbidities; and delirium education supports sense-making. Key mechanisms include personalised goal-setting, continuity of professional support, and integration with community services. The process evaluation within the feasibility trial confirmed the relevance and acceptability of these pathways, while suggesting refinements to training, psychosocial strategies, and education delivery. CONCLUSION: This paper provides an empirically grounded framework detailing the development and refinement of a programme theory for post-delirium rehabilitation, illustrating the value of flexible, theory-driven approaches to guiding recovery.

Authors

Institutions

Publication Details

Journal
PLoS ONE
Published
2026-03-31
DOI
https://doi.org/10.1371/journal.pone.0342149
Citations
1
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
Field-Weighted Citation Impact
20.93

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Developing a programme theory of a complex, home-based rehabilitation intervention for recovery after an episode of delirium

Sarah Joanna Richardson, Victoria A Goodwin, Louise Allan, Shruti Raghuraman et al.
1 citations
PLoS ONE
Intensive Care Unit Cognitive Disorders
20.93
article

Developing a programme theory of a complex, home-based rehabilitation intervention for recovery after an episode of delirium

Sarah Joanna Richardson, Victoria A Goodwin, Louise Allan, Shruti Raghuraman, Ellen H. Richards, Rowan Harwood, Annie Hawton, Obioha Chukwunyere Ukoumunne, Elizabeth Goodwin, Linda Clare, Alison Bingham, Roberta Anderson, Aseel Mahmoud, Sarah Morgan-Trimmer, Jinpil Um
article en
1 citations

Abstract

BACKGROUND: Delirium in older adults is associated with persistent cognitive and functional decline, increased institutionalisation, and higher mortality. Evidence-based strategies to support recovery after hospitalisation remain limited. This paper outlines the development and refinement of the programme theory underpinning RecoverED, a novel, home-based, multicomponent rehabilitation intervention designed to support post-delirium recovery. METHODS: We applied a realist-informed, multi-stage process to develop the RecoverED programme theory. This included a rapid realist review, qualitative interviews with older adults, carers, and healthcare professionals, an expert panel workshop, iterative programme theory meetings, and a process evaluation embedded within a single-arm feasibility trial. Data were synthesised into a logic model linking intervention components to hypothesised mechanisms and outcomes. RESULTS: The programme theory outlines how cognitive and physical rehabilitation, psychosocial support, health monitoring, lifestyle guidance, and delirium education are expected to promote recovery. Cognitive activities aim to rebuild executive function and daily independence; physical rehabilitation maintains mobility; psychosocial support reduces anxiety and promotes confidence; health monitoring and lifestyle guidance address comorbidities; and delirium education supports sense-making. Key mechanisms include personalised goal-setting, continuity of professional support, and integration with community services. The process evaluation within the feasibility trial confirmed the relevance and acceptability of these pathways, while suggesting refinements to training, psychosocial strategies, and education delivery. CONCLUSION: This paper provides an empirically grounded framework detailing the development and refinement of a programme theory for post-delirium rehabilitation, illustrating the value of flexible, theory-driven approaches to guiding recovery.

PLoS ONEVol. 21(3)
University of Nottingham (GB), University of Exeter (GB), Cumbria Northumberland Tyne and Wear NHS Foundation Trust (GB), Royal Devon & Exeter NHS Foundation Trust (GB), NIHR Newcastle Biomedical Research Centre (GB), Queen's Medical Centre (GB), University of Southampton (GB), Peninsula College of Medicine and Dentistry (GB)
National Institute for Health and Care Research, Department of Health and Social Care, University of Exeter, National Institute for Health Research Applied Research Collaboration South West Peninsula, Programme Grants for Applied Research, NIHR Newcastle Biomedical Research Centre
Openalex Percentile: Top 1%
Intensive Care Unit Cognitive Disorders
20.93
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.