Severe Thrombocytopenia and New Right Bundle Branch Block in Human Granulocytic Anaplasmosis: A Case Report

. The patient was initially treated empirically with atovaquone and azithromycin for presumed babesiosis, but therapy was narrowed to doxycycline with rapid recovery of symptoms and normalization of laboratory abnormalities. No echocardiogram or repeat electrocardiogram was performed during hospitalization despite the new conduction abnormality and elevated troponin, limiting conclusions regarding causality. This case underscores the need for heightened clinical suspicion in endemic regions, highlights an unusual severity of thrombocytopenia, and raises questions regarding potential cardiac involvement after the incidental finding of a new right bundle branch block.

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Publication Details

Journal
Journal of Brown Hospital Medicine
Published
2026-04-01
DOI
https://doi.org/10.56305/001c.158385
Primary Topic
Vector-borne infectious diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Severe Thrombocytopenia and New Right Bundle Branch Block in Human Granulocytic Anaplasmosis: A Case Report

Cynthia Zheng, Zachary Shaw
Journal of Brown Hospital Medicine
Vector-borne infectious diseases
article

Severe Thrombocytopenia and New Right Bundle Branch Block in Human Granulocytic Anaplasmosis: A Case Report

Cynthia Zheng, Zachary Shaw
article en

Abstract

. The patient was initially treated empirically with atovaquone and azithromycin for presumed babesiosis, but therapy was narrowed to doxycycline with rapid recovery of symptoms and normalization of laboratory abnormalities. No echocardiogram or repeat electrocardiogram was performed during hospitalization despite the new conduction abnormality and elevated troponin, limiting conclusions regarding causality. This case underscores the need for heightened clinical suspicion in endemic regions, highlights an unusual severity of thrombocytopenia, and raises questions regarding potential cardiac involvement after the incidental finding of a new right bundle branch block.

Journal of Brown Hospital MedicineVol. 5(2)
John Brown University (US)
Good health and well-being
Openalex Percentile: Top 26%
Vector-borne infectious diseases
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