Hapln1-HA signaling promotes progenitor cell proliferation and spinal cord regeneration
mediated progenitor cell proliferation. This study reveals that, in addition to lacking anti-regenerative ECM components around SC lesions, zebrafish can also leverage pro-regenerative ECM molecules to enhance progenitor cell potency and promote repair.
Authors
- Vishnu Muraleedharan Saraswathy (ORCID: https://orcid.org/0000-0003-4235-7051)
- Mayssa H. Mokalled (ORCID: https://orcid.org/0000-0002-3712-351X)
- Yuxiao Xu (ORCID: https://orcid.org/0000-0002-0802-845X)
- Lili Zhou
Institutions
- Washington University in St. Louis (US)
- Hope Center for Neurological Disorders (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-03-31
- DOI
- https://doi.org/10.64898/2026.03.28.714985
- Primary Topic
- Neurogenesis and neuroplasticity mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute of Neurological Disorders and Stroke