In Silico Design and Characterization of the Essential Outer-Membrane Lipoprotein LolB-Derived Multi-Epitope Vaccine Candidate Against Pseudomonas aeruginosa
and defines specific experimentally testable hypotheses for future in vitro/in vivo assessment. Essentiality-anchored epitope selection plus adjuvant-surface engineering yielded a structurally coherent, immunologically rational LolB-derived multi-epitope vaccine warranting experimental validation.
Authors
- Uchechukwu U. Nwodo (ORCID: https://orcid.org/0000-0003-0646-4028)
- Sinethemba H. Yakobi (ORCID: https://orcid.org/0000-0002-1048-039X)
Institutions
- University of Fort Hare (ZA)
Publication Details
- Journal
- Methods and Protocols
- Published
- 2026-04-01
- DOI
- https://doi.org/10.3390/mps9020052
- Primary Topic
- vaccines and immunoinformatics approaches
- Type
- article
- Field-Weighted Citation Impact
- 0.00