Temporal genomic dynamics of sequence type 39 Klebsiella pneumoniae in a neonatal unit in Blantyre, Malawi
ST39 lineages have a highly variable genome capable of incorporating large genomic regions during prolonged hospital circulation, which may offer a selective advantage in hospital environments and provide resistance to antimicrobial agents.
Authors
- Kondwani Kawaza (ORCID: https://orcid.org/0000-0002-9432-4916)
- Oliver Pearse (ORCID: https://orcid.org/0009-0000-6285-0893)
- Patrick Musicha (ORCID: https://orcid.org/0000-0001-7780-2173)
- Daryl Domman
- Zoe A. Dyson (ORCID: https://orcid.org/0000-0002-8887-3492)
- Eva Heinz
- Allan M. Zuza
- Nicholas A. Feasey
Institutions
- Los Alamos National Laboratory (US)
- University of Liverpool (GB)
- University of St Andrews (GB)
- University of Strathclyde (GB)
- Liverpool School of Tropical Medicine (GB)
- Malawi-Liverpool-Wellcome Trust Clinical Research Programme (MW)
- Kamuzu Central Hospital (MW)
- Wellcome Sanger Institute (GB)
- London School of Hygiene & Tropical Medicine (GB)
- Kamuzu University of Health Sciences (MW)
Publication Details
- Journal
- Microbial Genomics
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1099/mgen.0.001673
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bill and Melinda Gates Foundation
- Wellcome Trust
- Biotechnology and Biological Sciences Research Council