MR-SP <sup>2</sup> : A Microreactor-Based Workflow for Few-Cell Spatial Proteomics on the Legacy Zeiss PALM MicroBeam
improves identification depth for few-cell FFPE samples by nearly 3-fold compared to conventional tube-based workflows.
Authors
- Jan-Niklas Klatt (ORCID: https://orcid.org/0000-0001-6865-1545)
- Tobias Hutzenlaub (ORCID: https://orcid.org/0000-0001-6554-0604)
- Nils Paust (ORCID: https://orcid.org/0000-0003-0890-3709)
- Manuel Metzger
- Oliver Schilling
- Maximilian Maldacker
Institutions
- University of Freiburg (DE)
- University Medical Center Freiburg (DE)
- Hahn-Schickard-Gesellschaft für angewandte Forschung (DE)
Publication Details
- Journal
- Journal of Proteome Research
- Published
- 2026-03-31
- DOI
- https://doi.org/10.1021/acs.jproteome.5c01231
- Primary Topic
- Advanced Proteomics Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsches Krebsforschungszentrum
- Deutsche Forschungsgemeinschaft
- Bundesministerium für Bildung und Forschung
- Ministerium für Wirtschaft, Arbeit und Wohnungsbau Baden-Württemberg