Dynamic chemical bond-driven sustained release of GDN-PLGA microspheres in injectable composite hydrogels for enhanced wound healing
<0.01). Histological analysis showed more organized collagen deposition and increased vascular density. These results indicate that the GOA-GDN-PLGA injectable drug-loaded hydrogel facilitates rapid hemostasis and enables controlled drug release, effectively addressing the challenge of multiple administrations of soluble drugs in traditional wound management.
Authors
- Zhenxia Ma
- Yuanshou Zhu (ORCID: https://orcid.org/0000-0003-2711-1790)
- Ming Cao
- Dongdong Xiao
- Yinqi Dai
- Yamei Wang
- Zhigang Zhu
Institutions
- University of Shanghai for Science and Technology (CN)
- Renji Hospital (CN)
- Shanghai Institute of Technology (CN)
Publication Details
- Journal
- Biomedical Materials
- Published
- 2026-03-31
- DOI
- https://doi.org/10.1088/1748-605x/ae59dc
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Technology Commission of Shanghai Municipality