Anti-Ma2 Paraneoplastic Encephalitis and Testicular Cancer: When the Hypothalamus Whispers—A Case Report and Systematic Review with Emphasis on Hypothalamic-Endocrine Dysfunction
This study highlights the importance of recognizing hypothalamic-endocrine manifestations in PLE. In patients presenting with polydipsia and polyuria, CDI should be carefully differentiated from primary polydipsia using dynamic testing. Hypothalamic involvement may emerge years after tumor treatment, warranting long-term endocrine surveillance.
Authors
- Rossella Mazzilli (ORCID: https://orcid.org/0000-0001-6707-3413)
- Antongiulio Faggiano (ORCID: https://orcid.org/0000-0002-9324-3946)
- Bruno Giometto (ORCID: https://orcid.org/0000-0003-2311-9752)
- Flaminia Russo (ORCID: https://orcid.org/0000-0003-4703-4358)
- Virginia Zamponi (ORCID: https://orcid.org/0000-0002-2422-9673)
- Marco Zoccarato (ORCID: https://orcid.org/0000-0002-0182-6555)
- Piero Paravani
- Raffaele Iorio
- Alessandro Peri
- Marina Paola Gardiman
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Padua (IT)
- Ospedale Sant Antonio (IT)
- Provincia Autonoma di Trento (IT)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Medical Sciences
- Published
- 2026-03-31
- DOI
- https://doi.org/10.3390/medsci14020175
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00