Stem cell function <i>in vivo</i> is supported by an alternative glycolysis endpoint
does not require oxidation or fermentation but can terminate directly in pyruvate export, and this alternative pathway is sufficient to support stem cell function.
Authors
- Michalis Agathocleous (ORCID: https://orcid.org/0000-0002-3427-1023)
- Edward Owusu Kwarteng
- Yafeng Li
- Dieu Linh Nguyen
Institutions
- Children's Medical Center (US)
- Southwestern Medical Center (US)
- Southwestern Medical Center (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-04-01
- DOI
- https://doi.org/10.64898/2026.03.30.715412
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Welch Foundation
- Rally Foundation
- Cancer Prevention and Research Institute of Texas
- National Institutes of Health