Mechanisms of Action of Low-Frequency Pulsed Magnetic Fields in Pain Control

Low-frequency pulsed magnetic fields (LFPMFs) are a recently developed modality for managing pain and promoting wound healing. The term LFPMF is used to describe low-intensity fields in wound and tissue studies, and is referred to as magnetic peripheral nerve stimulation (mPNS) in pain-related studies. The recent clearance of the first mPNS device for treating pain due to diabetic neuropathy by the FDA marks a watershed event in the clinical acceptance of these modalities. In addition to being within the frequency range of 0.5-100 Hz, the use of electromagnetic fields rather than electrical current, which dissipates in tissues, results in several therapeutic advantages of magnetic fields. These fields permeate tissues and affect a larger area.