Photoinduced Deacylative Phosphorylation of Unstrained Ketones
The photoinduced deacylative transformation of ketones represents a powerful strategy for forming chemical bonds and developing innovative reactions. However, its potential application in deacylative phosphorylation remains unexplored. Herein, we report a metal-free, light-driven deacylative phosphorylation of unstrained ketones with diarylchlorophosphines, enabling the efficient synthesis of a wide variety of symmetrical and unsymmetrical tertiary phosphines. This method features mild conditions, operational simplicity, and broad substrate scope.
Authors
- Long Zhang (ORCID: https://orcid.org/0000-0002-4631-158X)
- Jimmy C. Yu (ORCID: https://orcid.org/0000-0001-9886-3725)
- Xiao‐Qiang Hu (ORCID: https://orcid.org/0000-0001-9094-2357)
- Xiaoyun Hu (ORCID: https://orcid.org/0000-0002-5251-2521)
- Linghe Li
- Yuan Chen
- Xiying Lai
Institutions
- Minzu University of China (CN)
- Kanto Chemical (Japan) (JP)
- Ministry of Education (PT)
Publication Details
- Journal
- Organic Letters
- Published
- 2026-03-31
- DOI
- https://doi.org/10.1021/acs.orglett.6c00848
- Primary Topic
- Organophosphorus compounds synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hubei Province
- South-Central University for Nationalities