Recombinant Expression and Automated Flow Synthesis of Fold-Switching Proteins Derived from <i>Streptococcus</i> Protein G
. Together, these methods provide benchmarks for dual chemical and biological preparations of fold-switching proteins, facilitating access to broader chemical space to study their structural and thermodynamic properties and to design new proteins with switchable properties for applications in science and medicine.
Authors
- Nicholas L. Truex (ORCID: https://orcid.org/0000-0002-7369-685X)
- Christian Marchal Golden
- Joanna Koryo Kwao (ORCID: https://orcid.org/0000-0003-0538-160X)
- Clara Kjerfve (ORCID: https://orcid.org/0000-0002-1665-7395)
- Jasmine Glover (ORCID: https://orcid.org/0009-0000-4509-6243)
- Bryson Wood
- Jordan Wolfe
Institutions
- University of South Carolina Sumter (US)
Publication Details
- Journal
- Biochemistry
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1021/acs.biochem.5c00800
- Primary Topic
- Protein Structure and Dynamics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Office of the Vice President for Research, University of South Carolina
- National Institute of General Medical Sciences
- Division of Chemistry