Inducible CreER <sup>T2</sup> Mouse Lines for Characterization of Retinal Bipolar Cell Subtypes

activity was observed in cone photoreceptor cells. ChR2EYFP expression was also detected in other ON and OFF cone bipolar cells, as well as rod bipolar cells, when tamoxifen induction was performed in the postnatal mice. These inducible Cre lines enable genetic manipulation in retinal bipolar cell subtypes at different developmental time points and serve as tools for elucidation of the mechanisms that control bipolar cell subtype development and function.

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Publication Details

Journal
eNeuro
Published
2026-04-01
DOI
https://doi.org/10.1523/eneuro.0483-25.2026
Primary Topic
Retinal Development and Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Inducible CreER T2 Mouse Lines for Characterization of Retinal Bipolar Cell Subtypes

Ebenezer Quainoo, Lotem Kol, Xiaoling Xie, Joseph Samson
eNeuro
Retinal Development and Disorders
article

Inducible CreER T2 Mouse Lines for Characterization of Retinal Bipolar Cell Subtypes

Ebenezer Quainoo, Lotem Kol, Xiaoling Xie, Joseph Samson
article en

Abstract

activity was observed in cone photoreceptor cells. ChR2EYFP expression was also detected in other ON and OFF cone bipolar cells, as well as rod bipolar cells, when tamoxifen induction was performed in the postnatal mice. These inducible Cre lines enable genetic manipulation in retinal bipolar cell subtypes at different developmental time points and serve as tools for elucidation of the mechanisms that control bipolar cell subtype development and function.

eNeuroVol. 13(4)
Augusta University (US), Augusta University Health (US)
Augusta University
Openalex Percentile: Top 29%
Retinal Development and Disorders
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