Natural Products Targeting Immune Mechanisms in Ocular Inflammation: Uveitis and Dry Eye
extracts, resveratrol and its derivatives, curcumin, and boswellic acids in experimental studies of ocular diseases. We particularly focus on their effects in alleviating ocular surface inflammation and intraocular inflammatory responses through their immunomodulatory mechanisms. This review aims to provide a mechanistic framework for understanding the potential role of natural products as complementary or alternative strategies to current therapeutic approaches, while informing the development of novel therapeutics and future research directions in ocular diseases.
Authors
- Jing Zhang (ORCID: https://orcid.org/0000-0002-3124-1101)
- Mingming Yang (ORCID: https://orcid.org/0009-0000-9161-9420)
- Yaru Zou
- Koju Kamoi
- Kyoko Ohno-Matsui
- Wenjia Lu
Publication Details
- Journal
- Current Issues in Molecular Biology
- Published
- 2026-04-01
- DOI
- https://doi.org/10.3390/cimb48040367
- Primary Topic
- Pharmacological Effects of Medicinal Plants
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Takeda Science Foundation
- Japan Agency for Medical Research and Development
- Japan Society for the Promotion of Science