MBD-Functionalized Magnetic Nanoparticles for Direct Enrichment of Plasma Methylated DNA in High-Sensitivity Liquid Biopsy
, SHOX2, RASSF1A, ZNF671, Septin9, and BMP3. Therefore, this study provides an efficient, universal and user-friendly enrichment and accurate detection of mDNA, laying a methodological foundation for early cancer screening and prognosis assessment.
Authors
- Cuiping Ma (ORCID: https://orcid.org/0000-0001-5491-7269)
- Xiangyu Chen (ORCID: https://orcid.org/0000-0001-6583-2295)
- Xiaowen Zhao
- Jiansen Du (ORCID: https://orcid.org/0009-0005-0419-9568)
- Ye Wang
- Yong Li
- Chao Shi
Institutions
- Qingdao University (CN)
- Qingdao University of Science and Technology (CN)
- Shenzhen International Travel Health Care Center (CN)
- Affiliated Hospital of Qingdao University (CN)
- Qingdao Municipal Hospital (CN)
- Detection Limit (United States) (US)
Publication Details
- Journal
- Analytical Chemistry
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1021/acs.analchem.6c00059
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shandong Province