Feasibility of low-biomass exhaled breath microbiome sequencing using a PDC-sampler in febrile and healthy individuals
. Functional annotations and diversity metrics revealed distinct microbial and metabolic patterns between individuals, confirming the platform's analytical sensitivity and biological representativeness. This work experimentally validates the feasibility of exhaled breath microbiome sequencing using the PDC-sampler, providing a practical and generalizable framework for noninvasive respiratory microecology studies and future diagnostic applications.
Authors
- Longhua Sun
- Dianhuai Meng (ORCID: https://orcid.org/0000-0002-9499-9366)
- Mengqing Cheng
- Manman Lv
- Yemin Han
- Quanjun Liu liu
- Zuhong Lu
- Xinping Xu
- Weihao Li
- Haotian Yu
- Yan Huang
Institutions
- Nanchang University (CN)
- Shenzhen University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- City University of Hong Kong, Shenzhen Research Institute (CN)
- First Affiliated Hospital of Nanchang University (CN)
- Southeast University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Journal of Breath Research
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1088/1752-7163/ae5a51
- Primary Topic
- Advanced Chemical Sensor Technologies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Shenzhen Fundamental Research Program