Prognostic Impact of Renin–Angiotensin System Inhibitors in Revascularized Patients with Acute Myocardial Infarction and Preserved or Mildly Reduced Ejection Fraction: A Retrospective Cohort Study

: In this single-center observational cohort of PCI-treated AMI survivors with LVEF ≥ 40%, discharge RASi therapy was associated with fewer HF rehospitalizations but not with lower overall mortality. Exploratory subgroup analyses suggested potential heterogeneity according to NSTEMI status and hypertension, but these findings should be considered hypothesis-generating and require confirmation.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-04-01
DOI
https://doi.org/10.3390/jcm15072676
Primary Topic
Acute Myocardial Infarction Research
Type
article
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article

Prognostic Impact of Renin–Angiotensin System Inhibitors in Revascularized Patients with Acute Myocardial Infarction and Preserved or Mildly Reduced Ejection Fraction: A Retrospective Cohort Study

Yongzhao Yao, Yanhua Yang, Lihua Chen, Xiaoyu Liu et al.
Journal of Clinical Medicine
Acute Myocardial Infarction Research
article

Prognostic Impact of Renin–Angiotensin System Inhibitors in Revascularized Patients with Acute Myocardial Infarction and Preserved or Mildly Reduced Ejection Fraction: A Retrospective Cohort Study

Yongzhao Yao, Yanhua Yang, Lihua Chen, Xiaoyu Liu, Minqi Liao, Z. Wang Jian, Suxia Guo, Zhiming Yuan
article en

Abstract

: In this single-center observational cohort of PCI-treated AMI survivors with LVEF ≥ 40%, discharge RASi therapy was associated with fewer HF rehospitalizations but not with lower overall mortality. Exploratory subgroup analyses suggested potential heterogeneity according to NSTEMI status and hypertension, but these findings should be considered hypothesis-generating and require confirmation.

Journal of Clinical MedicineVol. 15(7)
Third Affiliated Hospital of Southern Medical University (CN), Dongguan People’s Hospital (CN), Southern Medical University (CN)
Good health and well-being
Openalex Percentile: Top 28%
Acute Myocardial Infarction Research
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