Buffy Coat Enrichment Improves the Success Rate of Conventional Cytogenetics in Hypocellular Specimens: A Prospective Quality Improvement Study
: BCE significantly improves the success rate of chromosomal analysis by increasing the yield of metaphases in hypocellular specimens. This simple and scalable intervention reduces specimen rejection and enhances diagnostic yield in routine cancer cytogenetics.
Authors
- Gökçe Törüner (ORCID: https://orcid.org/0000-0002-5305-6337)
- Andrew M. McCoy (ORCID: https://orcid.org/0000-0003-0746-3756)
- Melissa Robinson (ORCID: https://orcid.org/0000-0001-9134-8632)
- Griselda Jazmin Cardona
- Su Yang
- L. Jeffrey Medeiros
- Guilin Tang
- Sarita S. Delgado
- Nawal Imtiaz
- Qing Wei
Institutions
- The University of Texas MD Anderson Cancer Center (US)
Publication Details
- Journal
- Genes
- Published
- 2026-03-31
- DOI
- https://doi.org/10.3390/genes17040417
- Primary Topic
- Genomic variations and chromosomal abnormalities
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Texas MD Anderson Cancer Center