Study on the Influence of Hydroxyapatite on Human Cell Viability and Adhesion in Chemical Antibacterial Silver Coatings

: The experimental study offers insights into the potential cytotoxic effects of silver in antibacterial coatings. Co-deposition with hydroxyapatite improved osteoblast viability compared to surfaces coated with silver alone, indicating that it may have a beneficial effect in Ag-based surface functionalization. The underlying mechanism (e.g., modulation of silver species/ion release) was not directly quantified in this work and should be addressed in future studies.

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Publication Details

Journal
Dentistry Journal
Published
2026-04-01
DOI
https://doi.org/10.3390/dj14040202
Primary Topic
Bone Tissue Engineering Materials
Type
article
Field-Weighted Citation Impact
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article

Study on the Influence of Hydroxyapatite on Human Cell Viability and Adhesion in Chemical Antibacterial Silver Coatings

M. Imre, Florin Miculescu, Lucian Toma Ciocan, Andreia Cucuruz et al.
Dentistry Journal
Bone Tissue Engineering Materials
article

Study on the Influence of Hydroxyapatite on Human Cell Viability and Adhesion in Chemical Antibacterial Silver Coatings

M. Imre, Florin Miculescu, Lucian Toma Ciocan, Andreia Cucuruz, Miruna Stan, Cosmin Mihai Cotrut, Ana Maria Tancu, Ionela Cristina Voinea, Vlad-Gabriel Vasilescu, Andreea Veronica Dediu-Botezatu, Elisabeta Vasilescu, Silviu Mirel Pițuru
article en

Abstract

: The experimental study offers insights into the potential cytotoxic effects of silver in antibacterial coatings. Co-deposition with hydroxyapatite improved osteoblast viability compared to surfaces coated with silver alone, indicating that it may have a beneficial effect in Ag-based surface functionalization. The underlying mechanism (e.g., modulation of silver species/ion release) was not directly quantified in this work and should be addressed in future studies.

Dentistry JournalVol. 14(4)
Romanian Space Agency (RO), University of Bucharest (RO), Carol Davila University of Medicine and Pharmacy (RO), "Dunarea de Jos" University of Galati (RO), Universitatea Națională de Știință și Tehnologie Politehnica București (RO)
Openalex Percentile: Top 36%
Bone Tissue Engineering Materials
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