A biomimetic nanodisc system selectively activates type I interferons by nonclassical STING pathway for cancer immunotherapy

stem cell-like T cells. We thus manifest a strategy based on STING therapy that does not depend on the ER and Golgi apparatus pathways to activate the IFN-I pathway, for cancer immunotherapy.

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Publication Details

Journal
Nature Communications
Published
2026-03-31
DOI
https://doi.org/10.1038/s41467-026-71363-6
Primary Topic
interferon and immune responses
Type
article
Field-Weighted Citation Impact
0.00
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article

A biomimetic nanodisc system selectively activates type I interferons by nonclassical STING pathway for cancer immunotherapy

Shuo Li, Xiunan Wang, D. T. Sun, Yue Xi et al.
Nature Communications
interferon and immune responses
article

A biomimetic nanodisc system selectively activates type I interferons by nonclassical STING pathway for cancer immunotherapy

Shuo Li, Xiunan Wang, D. T. Sun, Yue Xi, Xi Liu, Hao Liang, Haolan Deng, Xiaoyu An, Qianwen Mu
article en

Abstract

stem cell-like T cells. We thus manifest a strategy based on STING therapy that does not depend on the ER and Golgi apparatus pathways to activate the IFN-I pathway, for cancer immunotherapy.

Nature Communications
Shenzhen University (CN), Xiamen University (CN), Xiamen University of Technology (CN)
Good health and well-being
Openalex Percentile: Top 30%
interferon and immune responses
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