Hexafluoroisopropanol (HFIP)-Promoted Metal-Free Chemoselective <i>O</i> -Alkylation of 2-Pyridones with α-Halo Hydroxamates at Room Temperature
bond functionalization reactions. Overall, this operationally simple strategy enables rapid access to structurally diverse heterocyclic scaffolds that are of significant relevance to medicinal chemistry and drug discovery.
Authors
- Jeyakumar Kandasamy (ORCID: https://orcid.org/0000-0003-3285-971X)
- Aswathy Aniyan
Institutions
- Pondicherry University (IN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2026-04-01
- DOI
- https://doi.org/10.1021/acs.joc.5c03288
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science and Engineering Research Board