Compound‐Specific Stable Isotope Analysis Improves the Association Between Dairy Fatty Acid Biomarkers and Dairy Intake: A Secondary Analysis

C signature of 15:0 and 17:0 were measured in the dairy foods provided, and participants' plasma and red blood cells. We found that the isotopic signatures of plasma 15:0 and 17:0 were more enriched in the high-adherence group of participants in Halifax who consumed dairy (especially the DCR arm), and that these ratios were more similar to the signatures of the dairy food FA sources, thus reflecting dairy consumption. We also observed major differences in the content, composition, and isotopic signature of the target FA between the participants in Halifax and Toronto, which may be related to the different adherence rates, as well as to intrinsic geographic and dietary variations between populations. This study shows a potential use of compound-specific stable isotope analysis to provide more accurate information on dairy FA biomarkers reflecting consumption.

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Publication Details

Journal
Lipids
Published
2026-04-01
DOI
https://doi.org/10.1002/lipd.70053
Primary Topic
Isotope Analysis in Ecology
Type
article
Field-Weighted Citation Impact
0.00

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article

Compound‐Specific Stable Isotope Analysis Improves the Association Between Dairy Fatty Acid Biomarkers and Dairy Intake: A Secondary Analysis

Shirley Vien, Richard P. Bazinet, Camilla Parzanini, Bohdan L. Luhovyy et al.
Lipids
Isotope Analysis in Ecology
article

Compound‐Specific Stable Isotope Analysis Improves the Association Between Dairy Fatty Acid Biomarkers and Dairy Intake: A Secondary Analysis

Shirley Vien, Richard P. Bazinet, Camilla Parzanini, Bohdan L. Luhovyy, Priya Kathirvel, Marisa Soo, Ji‐Eun Chon, G. Harvey Anderson, Anthony J. Hanley
article en

Abstract

C signature of 15:0 and 17:0 were measured in the dairy foods provided, and participants' plasma and red blood cells. We found that the isotopic signatures of plasma 15:0 and 17:0 were more enriched in the high-adherence group of participants in Halifax who consumed dairy (especially the DCR arm), and that these ratios were more similar to the signatures of the dairy food FA sources, thus reflecting dairy consumption. We also observed major differences in the content, composition, and isotopic signature of the target FA between the participants in Halifax and Toronto, which may be related to the different adherence rates, as well as to intrinsic geographic and dietary variations between populations. This study shows a potential use of compound-specific stable isotope analysis to provide more accurate information on dairy FA biomarkers reflecting consumption.

Lipids
Mount Saint Vincent University (CA), University of Toronto (CA)
Dairy Farmers of Canada
Zero hunger
Openalex Percentile: Top 26%
Isotope Analysis in Ecology
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