Effects of Different Chemical Modifications on the Polysaccharide Structure, Antioxidant, and Whitening Activities of <i>Lavandula angustifolia</i> Mill

-induced oxidative stress by regulating malondialdehyde (MDA) content and the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px). Whitening activity experiments demonstrated that all derivatives were more effective than the native polysaccharide in reducing melanin content and tyrosinase activity. Among them, LAP-S exhibited the strongest inhibitory effect, reducing melanin content and tyrosinase activity by 56.49% ± 0.37% and 67.45% ± 0.32%, respectively, compared to the model group. In contrast, LAP-Se showed the weakest inhibitory effect, with melanin content and tyrosinase activity decreasing by only 37.77% ± 0.29% and 50.87% ± 0.35%, respectively, compared to the model group. This study indicates that LAP and its derivatives hold significant potential for application in the development of novel skincare products.

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Publication Details

Journal
Chemistry & Biodiversity
Published
2026-04-01
DOI
https://doi.org/10.1002/cbdv.71183
Primary Topic
Polysaccharides and Plant Cell Walls
Type
article
Field-Weighted Citation Impact
0.00
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article

Effects of Different Chemical Modifications on the Polysaccharide Structure, Antioxidant, and Whitening Activities of Lavandula angustifolia Mill

Wei Feng, Yuhao Cui, Yonggang Lin, Jie Li et al.
Chemistry & Biodiversity
Polysaccharides and Plant Cell Walls
article

Effects of Different Chemical Modifications on the Polysaccharide Structure, Antioxidant, and Whitening Activities of Lavandula angustifolia Mill

Wei Feng, Yuhao Cui, Yonggang Lin, Jie Li, Conghui Ren
article en

Abstract

-induced oxidative stress by regulating malondialdehyde (MDA) content and the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px). Whitening activity experiments demonstrated that all derivatives were more effective than the native polysaccharide in reducing melanin content and tyrosinase activity. Among them, LAP-S exhibited the strongest inhibitory effect, reducing melanin content and tyrosinase activity by 56.49% ± 0.37% and 67.45% ± 0.32%, respectively, compared to the model group. In contrast, LAP-Se showed the weakest inhibitory effect, with melanin content and tyrosinase activity decreasing by only 37.77% ± 0.29% and 50.87% ± 0.35%, respectively, compared to the model group. This study indicates that LAP and its derivatives hold significant potential for application in the development of novel skincare products.

Chemistry & BiodiversityVol. 23(4)
Yili Normal University (CN)
Openalex Percentile: Top 29%
Polysaccharides and Plant Cell Walls
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