Blackened Panax quinquefolius L. Saponins and Their Cytotoxic Effect on HepG2 Cells

values of 0.2999 mg/mL and 0.2640 mg/mL, respectively, as well as stronger reducing power. Meanwhile, BPQS exhibited higher cytotoxicity toward HepG2 cells and effectively inhibited cell survival and proliferation by promoting the expression of apoptosis-related proteins, including caspase 3 and caspase 9. Our findings indicate that BPQS may be a functional ingredient suitable for use in dietary supplements and disease chemoprevention.

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Publication Details

Journal
Molecules
Published
2026-04-01
DOI
https://doi.org/10.3390/molecules31071173
Primary Topic
Ginseng Biological Effects and Applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Blackened Panax quinquefolius L. Saponins and Their Cytotoxic Effect on HepG2 Cells

Yuanyuan Tian, Yongqi Liu, Jiaqi Gao
Molecules
Ginseng Biological Effects and Applications
article

Blackened Panax quinquefolius L. Saponins and Their Cytotoxic Effect on HepG2 Cells

Yuanyuan Tian, Yongqi Liu, Jiaqi Gao
article en

Abstract

values of 0.2999 mg/mL and 0.2640 mg/mL, respectively, as well as stronger reducing power. Meanwhile, BPQS exhibited higher cytotoxicity toward HepG2 cells and effectively inhibited cell survival and proliferation by promoting the expression of apoptosis-related proteins, including caspase 3 and caspase 9. Our findings indicate that BPQS may be a functional ingredient suitable for use in dietary supplements and disease chemoprevention.

MoleculesVol. 31(7)
Tianjin University of Science and Technology (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 35%
Ginseng Biological Effects and Applications
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