Blackened Panax quinquefolius L. Saponins and Their Cytotoxic Effect on HepG2 Cells
values of 0.2999 mg/mL and 0.2640 mg/mL, respectively, as well as stronger reducing power. Meanwhile, BPQS exhibited higher cytotoxicity toward HepG2 cells and effectively inhibited cell survival and proliferation by promoting the expression of apoptosis-related proteins, including caspase 3 and caspase 9. Our findings indicate that BPQS may be a functional ingredient suitable for use in dietary supplements and disease chemoprevention.
Authors
- Yuanyuan Tian (ORCID: https://orcid.org/0000-0002-1119-1231)
- Yongqi Liu
- Jiaqi Gao
Institutions
- Tianjin University of Science and Technology (CN)
Publication Details
- Journal
- Molecules
- Published
- 2026-04-01
- DOI
- https://doi.org/10.3390/molecules31071173
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China