Atypical Imaging Features of Primary Peritoneal High-Grade Serous Carcinoma

A 57-year-old woman presented with fever was incidentally found to have a large hepatogastric space mass with coarse calcifications on CT, accompanied by a markedly elevated serum CA-125 level (3082 U/mL). 18F-FDG PET/MR revealed intense metabolic activity (SUVmax= 10.82) and restricted diffusion without ascites, while both ovaries appeared unremarkable. Pathology confirmed primary peritoneal high-grade serous carcinoma (PPHGSC). This case illustrates atypical imaging features of this rare malignancy, including lesion localization, coarse calcification, and absence of ascites.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2026-04-01
DOI
https://doi.org/10.1097/rlu.0000000000006398
Primary Topic
Intraperitoneal and Appendiceal Malignancies
Type
article
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article

Atypical Imaging Features of Primary Peritoneal High-Grade Serous Carcinoma

Xinwei Cheng, Jian Zhang, Jie Ding, Jun Zhao et al.
Clinical Nuclear Medicine
Intraperitoneal and Appendiceal Malignancies
article

Atypical Imaging Features of Primary Peritoneal High-Grade Serous Carcinoma

Xinwei Cheng, Jian Zhang, Jie Ding, Jun Zhao, Haiyan Wang
article en

Abstract

A 57-year-old woman presented with fever was incidentally found to have a large hepatogastric space mass with coarse calcifications on CT, accompanied by a markedly elevated serum CA-125 level (3082 U/mL). 18F-FDG PET/MR revealed intense metabolic activity (SUVmax= 10.82) and restricted diffusion without ascites, while both ovaries appeared unremarkable. Pathology confirmed primary peritoneal high-grade serous carcinoma (PPHGSC). This case illustrates atypical imaging features of this rare malignancy, including lesion localization, coarse calcification, and absence of ascites.

Clinical Nuclear MedicineVol. 51(5)
Dalian Medical University (CN), Shanghai East Hospital (CN)
Good health and well-being
Openalex Percentile: Top 7%
Intraperitoneal and Appendiceal Malignancies
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