Tumor-Induced Osteomalacia Localized to an Abdominal Wall Phosphaturic Mesenchymal Tumor by 68Ga-DOTATATE PET/CT

A ⁶⁸Ga-DOTATATE PET/CT scan was performed on a 40-year-old woman with suspected tumor-induced osteomalacia (TIO), who presented with progressive bone pain, multiple fractures, and hypophosphatemia. The scan revealed a solitary focus of intense somatostatin receptor avidity within the right lower abdominal wall musculature. No other suspicious lesions were identified. On the basis of this finding, the tumor was surgically resected, and histopathology confirmed a phosphaturic mesenchymal tumor (PMT). Postoperatively, the patient's serum phosphate levels normalized. This case underscores the paramount value of ⁶⁸Ga-DOTATATE PET/CT in localizing occult PMTs, even in uncommon locations like the abdominal wall, guiding definitive surgical management.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2026-04-01
DOI
https://doi.org/10.1097/rlu.0000000000006399
Primary Topic
Parathyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Tumor-Induced Osteomalacia Localized to an Abdominal Wall Phosphaturic Mesenchymal Tumor by 68Ga-DOTATATE PET/CT

Shuo Hu, TingTing Long, JiaYu Zhong
Clinical Nuclear Medicine
Parathyroid Disorders and Treatments
article

Tumor-Induced Osteomalacia Localized to an Abdominal Wall Phosphaturic Mesenchymal Tumor by 68Ga-DOTATATE PET/CT

Shuo Hu, TingTing Long, JiaYu Zhong
article en

Abstract

A ⁶⁸Ga-DOTATATE PET/CT scan was performed on a 40-year-old woman with suspected tumor-induced osteomalacia (TIO), who presented with progressive bone pain, multiple fractures, and hypophosphatemia. The scan revealed a solitary focus of intense somatostatin receptor avidity within the right lower abdominal wall musculature. No other suspicious lesions were identified. On the basis of this finding, the tumor was surgically resected, and histopathology confirmed a phosphaturic mesenchymal tumor (PMT). Postoperatively, the patient's serum phosphate levels normalized. This case underscores the paramount value of ⁶⁸Ga-DOTATATE PET/CT in localizing occult PMTs, even in uncommon locations like the abdominal wall, guiding definitive surgical management.

Clinical Nuclear MedicineVol. 51(5)
Central South University (CN), National Clinical Research (US), Xiangya Hospital Central South University (CN)
Good health and well-being
Openalex Percentile: Top 24%
Parathyroid Disorders and Treatments
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