Psychiatrist’s Perspective on Drug Overdose and the Expected Role of Pharmacists

Suicide remains a critical public health challenge in Japan, with the interaction between physical illness and psychiatric comorbidity emerging as a major determinant of risk. Patients with serious medical conditions face markedly elevated rates of suicidal behavior, particularly when depression or alcohol use disorders are present. Conventional preventive strategies, including screening and provider education, have yielded only modest effects. In contrast, collaborative care models that integrate psychiatrists, primary care physicians, and pharmacists demonstrate superior efficacy, significantly reducing suicidal ideation and attempts. Case management further enhances treatment adherence and clinical outcomes. Internationally, pharmacists play a pivotal role in medication management and suicide risk monitoring; however, in Japan their involvement remains limited by insufficient psychiatric training, institutional constraints, and inadequate reimbursement systems. Addressing these barriers through enhanced education, supportive policy reforms, and structured collaborative care frameworks could expand their role in suicide prevention. A comprehensive, multidisciplinary approach that strengthens pharmacist engagement may contribute substantially to reducing suicide risk among physically ill patients in Japan.

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Publication Details

Journal
YAKUGAKU ZASSHI
Published
2026-03-31
DOI
https://doi.org/10.1248/yakushi.25-00163-2
Primary Topic
Suicide and Self-Harm Studies
Type
article
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article

Psychiatrist’s Perspective on Drug Overdose and the Expected Role of Pharmacists

Yasuhiro Kishi, Takahiro Takeuchi, Kana Yamamoto
YAKUGAKU ZASSHI
Suicide and Self-Harm Studies
article

Psychiatrist’s Perspective on Drug Overdose and the Expected Role of Pharmacists

Yasuhiro Kishi, Takahiro Takeuchi, Kana Yamamoto
article en

Abstract

Suicide remains a critical public health challenge in Japan, with the interaction between physical illness and psychiatric comorbidity emerging as a major determinant of risk. Patients with serious medical conditions face markedly elevated rates of suicidal behavior, particularly when depression or alcohol use disorders are present. Conventional preventive strategies, including screening and provider education, have yielded only modest effects. In contrast, collaborative care models that integrate psychiatrists, primary care physicians, and pharmacists demonstrate superior efficacy, significantly reducing suicidal ideation and attempts. Case management further enhances treatment adherence and clinical outcomes. Internationally, pharmacists play a pivotal role in medication management and suicide risk monitoring; however, in Japan their involvement remains limited by insufficient psychiatric training, institutional constraints, and inadequate reimbursement systems. Addressing these barriers through enhanced education, supportive policy reforms, and structured collaborative care frameworks could expand their role in suicide prevention. A comprehensive, multidisciplinary approach that strengthens pharmacist engagement may contribute substantially to reducing suicide risk among physically ill patients in Japan.

YAKUGAKU ZASSHIVol. 146(4)
Nippon Medical School (JP)
Good health and well-being
Openalex Percentile: Top 6%
Suicide and Self-Harm Studies
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Psychiatrist’s Perspective on Drug Overdose and the Expected Role of Pharmacists — Yasuhiro Kishi, Takahiro Takeuchi, et al. · YAKUGAKU ZASSHI (2026) | TGRS Research Map | TGRS