Sex Differences in Psychotropic Drug Exposure and Safety: A Systematic Review Toward Personalized Dosing Strategies

: Sex influences psychotropic drug exposure, pharmacodynamic sensitivity, and safety profiles in ways that may be clinically relevant. Integrating sex-aware considerations into dosing strategies could improve therapeutic precision and reduce adverse outcomes, reinforcing the importance of sex as a key variable in personalized psychiatric care.

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Publication Details

Journal
Journal of Personalized Medicine
Published
2026-03-31
DOI
https://doi.org/10.3390/jpm16040189
Primary Topic
Sex and Gender in Healthcare
Type
article
Field-Weighted Citation Impact
0.00
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article

Sex Differences in Psychotropic Drug Exposure and Safety: A Systematic Review Toward Personalized Dosing Strategies

Giuseppe Albano, Stefania Zerbo, Maria Puntarello, Antonina Argo et al.
Journal of Personalized Medicine
Sex and Gender in Healthcare
article

Sex Differences in Psychotropic Drug Exposure and Safety: A Systematic Review Toward Personalized Dosing Strategies

Giuseppe Albano, Stefania Zerbo, Maria Puntarello, Antonina Argo, Ginevra Malta
article en

Abstract

: Sex influences psychotropic drug exposure, pharmacodynamic sensitivity, and safety profiles in ways that may be clinically relevant. Integrating sex-aware considerations into dosing strategies could improve therapeutic precision and reduce adverse outcomes, reinforcing the importance of sex as a key variable in personalized psychiatric care.

Journal of Personalized MedicineVol. 16(4)
Department of Health (ES)
Openalex Percentile: Top 27%
Sex and Gender in Healthcare
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