Microbial profiling of five traditional Chinese medicines: culture-based identification vs. 16S rRNA sequencing
Sequencing uncovered substantially broader microbial diversity than culture-based methods, while both approaches identified pathogenic and opportunistic microbes. These findings emphasize the critical need for more rigorous microbial surveillance and stringent quality control of TCMs to protect public health.
Authors
- Bingshu Wang (ORCID: https://orcid.org/0000-0002-2603-8328)
- Banzhan Ruan (ORCID: https://orcid.org/0000-0001-9749-5203)
- Qibing Liang (ORCID: https://orcid.org/0009-0002-0184-0135)
- Shi Li
- Le Du
- Chunyan Feng
- Shaojiang Zheng
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Analysis and Testing Centre (CN)
- Hainan Center for Disease Control & Prevention (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- Journal of Medical Microbiology
- Published
- 2026-03-31
- DOI
- https://doi.org/10.1099/jmm.0.002137
- Primary Topic
- Enterobacteriaceae and Cronobacter Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hainan Medical University
- Center for Depression Research and Clinical Care, University of Texas Southwestern Medical Center